Dr David Sinclair: Can Aging Be Reversed? After 8 Weeks, Cells Appeared 75% Younger In Tests!

This is very uh

It's bad, right? It's hard, yeah.

>> That's what it's like to be old. And for

far too long, we've ignored [music] it

or accepted it as natural. And I reject

the idea that aging, just because it's

natural, is acceptable. Dying at 80 is

not inevitable. Absolutely, that can be

changed. So, if you're skeptical, I am a

Harvard professor who has been studying

aging, longevity, and age reversal for

30 years. And I've seen enough from my

lab showing that we can literally now

reverse the aging process. And it's not

a question of if, it's [music] a

question of when this is going to And

everyone should stick around cuz I'm

going to tell you some of the major

things that people should be doing. They

can lengthen your life by a decade. Hey,

you're not taking that off, Steven.

You've got 10 minutes of that. So, you

can accelerate aging by smoking, getting

an X-ray, ultra-processed foods,

excessive drinking, flying a lot. I fly

all the time. That's probably

accelerating your aging process.

Even going to a rock concert and

blasting your eardrums because your ear

hair cells are getting [music] older

faster. And so, I look at the body like

it's a computer and we can reinstall the

software. And what's [music] interesting

is when you reverse aging, diseases like

Alzheimer's, cancer, heart disease go

away [music] or are cured. Because

what's driving a lot of those diseases

is aging. And so, my lab is like Willy

Wonka's chocolate factory. They are

making discoveries that blow me away

every week. And I think we're at a

turning point in human history [music]

where you're probably going to live into

the 22nd century if you do all the right

things. And we're going to dig into all

of those in great detail. But what are

the unintended consequences of such a

world where we all live longer? And

also, do you think it's going to be

possible in the next 50 years for us to

live forever? And then, what's the best

uh treatment you've discovered for hair

loss?

>> This is why I love your podcast, Steven.

You ask the right questions. So, first

of

This is super interesting to me. My team

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If you are a regular viewer of this show

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my team, everyone here, to keep this

show free, to keep it improving year

over year and week over week, it is just

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double-check if you've hit it. Only

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Do we have a deal?

If you do it, I'll tell you what I'll

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we fight harder and harder and harder

and harder to bring you the guests and

conversations that you want to hear. I

stayed true to that promise since the

very beginning of the Diary of a CEO,

and I will not let you down. Please help

us. Really appreciate it. Let's get on

with the show.

>> [music]

>> Dr. David Sinclair. I have waited many

years to speak to you. And I've been so

keen to speak to you for so many years

because

so much of the research and the

information I've consumed on the

subjects we're going to talk about today

comes from you, directly from research

you've done, and from theories and ideas

and hypotheses that you formed. I think

the place that this conversation should

start is

is probably with this picture because it

appears to be incredibly formative

in your journey.

Oh, yes.

That is an important picture, true.

This is a picture

of my grandmother and me when I was in

my early 20s, I'm now 56, if you're

wondering.

And uh my grandmother has played a major

role in my life. Uh I'm going to have to

be careful not to get too emotional

because uh she's now passed passed away,

but she's inspired

me to

do the best I can to leave the world a

better place than uh I found it.

And there's this particular book here

called Now We Are Six.

It is Anyone who's read my book uh

Lifespan knows that this book is very

important to me. And I didn't realize

it, of course, when I was a kid that

this was going to change my whole life.

And there's a poem at the back there

that my grandmother, Vera, used to read

me

when I was six.

And it goes like this. When I was one, I

had just begun. When I was two, I was

nearly new. When I was three, I was

hardly me.

When I was four, I was not much more.

When I was five, I was just alive.

But now, I am six.

I'm as clever as clever. So, I think

I'll be six now forever and ever.

I'm getting chills reading this again

and hearing this poem again because

the impact on me was the following, that

subconsciously, my grandmother was

saying, "You you don't want to grow up.

Adults can be evil." She grew up after

World War II.

There was horrendous uh

impact on her and her family in Hungary.

And she thought that a child is innocent

and people shouldn't grow up. But what

actually happened was I realized

why do people grow old?

That's a terrible thing to happen. And

so, I've spent my life

trying to figure out why do we get old?

Why do we grow up? Why do we get frail?

Because I also think that if we can

solve that, understand it,

slow it, even reverse it now,

we we'll have the biggest impact on

human health in history.

Am I right in thinking your grandmother

told you at that young age that she was

going to die, that you were going to

die, that your parents were going to

die? Yes, uh she did tell me that. I

remember it very clearly, actually. I

was on the floor and she was crouching

down and I said, "Vera." I didn't call

her

grandma. She didn't want to be called

grandma. She wanted to be young like a

kid to me. I said, "Vera, will will you

always be here to protect me? Will you

always be around?" She said, "No, I'm

going to die."

I'm like, "What do you mean?" She goes,

"Every everything dies. I'm going to be

gone.

Your parents will be gone. Your pet cat

will be dead pretty soon. And you

yourself will be dead one day."

At age, you know, four or five, that's

that's that's heart-wrenching, right?

We've all gone through this realization

around that age that the world that we

believe in and see will one day all be

gone. That moment, I remember it so

clearly because I thought, "That's not

fair. Why would any species be made or

created that knew that fact? That's

cruel. It's better to either not know

or to not exist. But to know that that's

what's going to happen

is really cruel. And so, I I I vowed

actually legitimately around the age of

18

to get a PhD, to go to the United

States,

and develop a research lab to try and

do something about it. The preservation